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Team LRN Amoxapine Similar to the tricyclics with the addition of some effects associated with the antipsychotics (Chapter 29: Antipsychotic Agents Lithium) Maprotiline Similar to tricyclics; seizures are dose-related Mirtazapine Somnolence, increased appetite, weight gain, dizziness Trazodone, nefazadone Drowsiness, dizziness, insomnia, nausea, agitation Venlafaxine Nausea, somnolence, sweating, dizziness, sexual disturbances, hypertension, anxiety Bupropion Dizziness, dry mouth, sweating, tremor, aggravation of psychosis, potential for seizures at high doses Fluoxetine and other serotonin reuptake inhibitors Gastrointestinal symptoms, decreased libido, tradkng dysfunction, anxiety (acutely), insomnia, tremor Drug Interactions Pharmacodynamic Interactions Many of the pharmacodynamic interactions of antidepressants with other drugs have already been discussed.

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