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Nerve and muscle cells, like most other cells under in vivo conditions, have a very large inward driving force onNa ions(Vm 0,VNa 0;sothatVm VNa isverymuchlessthan0)and a small outward driving force on K ions (Vm is normally just a little greater than VK, so that Vm VK is only just a little greater than 0) at typical membrane poten- tials (70 to 90 mV).

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